- Four new Litagion agent profiles and a new theme summarizing CoMeta content related to infertility
- New blog content: "Declining sperm quality, delayed childbearing, and the cost of assisted reproductive technology"
- Updated Litagion agent and company profiles impacted by newly published peer-reviewed science and newly gathered company information
- Infertility. Infertility is typically defined as the inability to conceive after one year of unprotected sex or the inability to carry a pregnancy to term. Male-factor infertility may result from low sperm count or abnormal sperm motility and morphology. Female-factor infertility results from problems with ovulation and the ovaries (e.g., polycysticovary syndrome), the fallopian tubes (e.g., endometriosis), or uterus (e.g., fibroids). Infertility has many causes (age being the most common), but scientists are increasingly focused on environmental factors and the detrimental impact of endocrine disrupting chemicals in particular.
- Caffeine. A central nervous stimulant naturally occurring in coffee, tea, and chocolate. Caffeine is added to food and beverages, cosmetics, and personal care products. It's also regulated as an active pharmaceutical ingredient.
- Carbon black. Often added to products as a colorant, carbon black also imparts flexibility and abrasion resistance.
- Palladium nanoparticles. Palladium nanoparticles measure less than 100 nanometers in any dimension and are predominately used as a chemical catalyst.
- Propyl gallate. A synthetic chemical used as a food additive to prevent oxidation.
Updated Litagion agents based on newly published science
All Litagion agent profiles have been updated to reflect the most recently published peer-reviewed science. Notable scientific studies added to CoMeta since the last release include:
- Mercury. A National Nutrition and Healthy survey in Taiwan links mercury levels found in red blood cells to type 2 diabetes.
- Perfluorooctanesulfonic acid. The POUNDS-LOST study links PFOS to significantly lower bone mineral density.
In addition, we highlight the following changes to the components of Litagion agent risk resulting from recently published peer-reviewed science:
|Risk category change
|Overall risk change
|Projected science risk changes from Low (green) to Medium-low (light green)
|Projected science risk changes from Medium-high (orange) to High (red)